Molecular therapies for systemic lupus erythematosus: clinical trials and future prospects

نویسندگان

  • Fanny Monneaux
  • Sylviane Muller
چکیده

The prognosis of patients with systemic lupus erythematosus has greatly improved since treatment regimens combining corticosteroids and immunosuppressive medications have been widely adopted in therapeutic strategies given to these patients. Immune suppression is evidently efficient but also leads to higher susceptibility to infectious and malignant diseases. Toxic effects and sometimes unexpectedly dramatic complications of current therapies have been progressively reported. Identifying novel molecular targets therefore remains an important issue in the treatment of lupus. The aim of this review article is to highlight emerging pharmacological options and new therapeutic avenues for lupus with a particular focus on non-antibody molecular strategies.

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عنوان ژورنال:
  • Arthritis Research & Therapy

دوره 11  شماره 

صفحات  -

تاریخ انتشار 2009